Time is the most critical factor
Bloodstream infections and the resulting sepsis are among the most common causes of
morbidity and mortality in hospitals. What decides the outcome is the early
identification of the causative pathogen and its resistance profile — only then can
antimicrobial therapy be targeted.
Blood culture remains the gold standard, but incubation and subculturing often mean one
to several days to a result. That delay is especially critical in patients with
hard-to-culture or slow-growing pathogens — or when antimicrobial therapy has already
started.
Molecular diagnostics straight from whole blood
Molecular tests can substantially shorten the time to result. cube dx’s compact
sequencing identifies clinically relevant bacteria, fungi and resistance genes
directly from whole blood in under three hours — with no prior culturing.
This approach is particularly valuable for:
- Mixed infections, where several pathogens must be detected in parallel
- Slow- or non-growing microorganisms
- Situations where antimicrobial therapy is already under way
A complement, not a replacement
Molecular tests don’t replace blood culture — they add speed to it. In independent
clinical studies, the hybcell technology showed advantages over established methods
particularly for mixed infections and the rapid detection of relevant resistance markers.
See the details in our publications.