The future of in-vitro diagnostics

Fight infections.
Diagnose early.

Cube Dx' compact sequencing identifies a vast range of clinically relevant pathogens directly from whole blood and other sample matrices - in less than 3 hours. For early, targeted antimicrobial therapy of blood stream and other severe infections.

hyborg Dx RED
hyborg Dx delivers results directly from whole blood — in less than 3 hours.
Why it matters

Early results - optimised therapy

Earlier to result

Comprehensive pathogen ID directly from whole blood and other sample matrices in less than 3 hours — no culturing required.

Additional results

Additional results from DNA-based detection of pathogens that are difficult to culture (fungi, fastidious bacteria, anaerobes) or for patients who have already undergone treatment.

Versatile multiplexing

Sepsis, other severe infections (pneumonia, etc.), or general 16S/28S amplicon sequencing—the same platform, the same products, multiple applications.

Whole blood
blood stream infections
82
pathogens & resistance genes
< 3
hours to result
BAL
pneumonia
31
pathogens
< 2
hours to result
Positive blood culture
microbial infections
95
pathogens & resistance genes
< 2
hours to result
The workflow

From sample to result

Example microbial ID: A comprehensive system including sample preparation, sensitive PCR and microarray identification. No plating, no culturing, no waiting.

01
0 to 0.3 h

Sample preparation

Microorganisms are enriched and efficiently lysed - from whole blood, tissue, body fluids or respiratory specimens.

02
~1.75 h

DNA extraction & detection

Purification / extraction of DNA and pan-bacterial 16S and pan-fungal 28S PCR to separate negative from positive samples.

03
~0.3 h

Identification

Positive samples are examined with hybcell against many targets in parallel. hyborg Dx RED processes and analyses completely automatically and wraps results up in a comprehensive report.

Technological leap

compact sequencing - We build technology

compact sequencing combines ultra-sensitive PCR with the rapid and precise identification of microorganisms using the hybcell. It offers massive multiplexing with simple, robust handling and rapid results.

  • Parallel identification of 200+ DNA targets from one sample
  • Combines PCR-based screening with detailed analysis of positive samples in a single workflow
  • A robust, straightforward workflow with automated analysis for routine diagnostics
Get in touch

Let's get in touch

If you have any questions about Cube Dx, compact sequencing, or our products, or if you're interested in a demo, please contact us.

Bernhard Ronacher, Management, cube dx